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Cystic fibrosis (CF) is a multi-organ disease, affecting mostly lungs and gastrointestinal tract.
An 18-months study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis. A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cysticfibrosis. Emerging new therapies are targeted at all points in the pathogenesis of lung disease, from drugs that treat infection and inflammation in the airways to gene transfer studies and to drugs that augment airway surface liquid height. The impact of early cystic fibrosis diagnosis on pulmonary function in children. A number of antibacterial agents formulated for inhalation are at various stages of study and there are several anti-inflammatory candidate drugs in clinical trials. Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. Stratified assessment of the role of inhaled hypertonic saline in reducing cystic fibrosis pulmonary exacerbations: a retrospective analysis. Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study.